At least 35 people were wounded in the chaos during a concert by popular musician Sfera Ebbasta at the Lanterna Azzurra nightclub in Corinaldo, Italian news agency ANSA reported.
It appears the panic began when someone in the club sprayed an “irritant substance,” leading to a stampede, the civil protection agency tweeted.
Five teenagers and a woman who had accompanied her daughter to the concert were killed, said Luigi Di Maio, the Italian deputy prime minister. He identified those killed as Asia Nasoni, 14; Daniele Pongetti, 16; Benedetta Vitali, 15; Mattia Orlandi,15; Emma Fabini, 14; and 39-year-old Eleonora Girolimini.
“These (victims) are young people. It’s absurd to die this way. As a government we will do everything we can to clarify the circumstances and make sure the security norms were followed,” Maio posted on Facebook.
Numerous paramedics were seen treating concertgoers on the street following the stampede.
Corinaldo is in the eastern coast province of Ancora and about 90 miles (145 km) east of Florence